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M94A0699.TXT
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1994-10-21
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Document 0699
DOCN M94A0699
TI HIV related Mycobacterium tuberculosis (M.Tb) at Fairfield Hospital.
DT 9412
AU Wright EJ; Sarr A; Dwyer B; Hoy J; Fairfield Hospital, Vic.
SO Annu Conf Australas Soc HIV Med. 1993 Oct 28-30;5:32 (abstract no. FC1).
Unique Identifier : AIDSLINE ASHM5/94348956
AB OBJECTIVE: To review the clinical and laboratory features, management
and outcome of M.tuberculosis in 18 HIV seropositive patients (2.5% of
the total AIDS patients). METHODS: A retrospective review of case
records and laboratory results of 16 male and 2 female patients
attending Fairfield Hospital between January 1985 and June 1993. The
median age at presentation was 35 years (25-61 years) and 6 patients
(33%) had no identifiable risk factors for TB. In 13/18 patients (72%),
TB was the AIDS defining illness. There was less delay in the diagnosis
of pulmonary TB than extrapulmonary TB (see table). 4/18 were treated
presumptively for MAC infection prior to isolation of M.Tb. All isolates
were fully sensitive to standard TB drugs and treatment was well
tolerated. 9/18 patients have died and the median survival in the 8/9
patients diagnosed antemortem was 949 days (R173-1,724 days).
CONCLUSION: TB occurs in advanced HIV disease, the diagnosis may be
delayed, treatment is well tolerated and median survival is greater than
2.5 years. TABULAR DATA, SEE ABSTRACT VOLUME.
DE Adult AIDS-Related Opportunistic Infections/DIAGNOSIS/*EPIDEMIOLOGY
Cross-Sectional Studies Female Human Incidence Male Middle Age
Retrospective Studies Tuberculosis, Pulmonary/DIAGNOSIS/*EPIDEMIOLOGY
Victoria/EPIDEMIOLOGY MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).